Resignation

Ref: Syn/CS/SE/Reg 30/2026-27/Jul/08 Syngene International Limited Biocon SEZ, Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area, IV Phase, Jigani Link Road, Bengaluru 560 099, Karnataka, India T +91 80 6891 9191 CIN: L85110KA1993PLC014937 July 08, 2026 www.syngeneintl.com To, To, The Manager, The Manager, BSE Limited National Stock Exchange of India Limited Corporate Relationship Department Corporate Communication Department Dalal Street, Mumbai – 400 001 Bandra (EAST), Mumbai – 400 051 Scrip Code: 539268 Scrip Symbol: SYNGENE Dear Sir/Madam, Subject: Intimation under Regulation 30 of SEBI (Listing Obligations & Disclosure Requirements) Regulations 2015 – Resignation of Statutory Auditor of material subsidiary. Pursuant to Regulation 30 of SEBI (Listing Obligations and Disclosure Requirements) Regulations, 2015 read with SEBI Master Circular No. HO/49/14/14(7)2025-CFD-POD2/I/3762/2026 dated January 30, 2026, we wish to inform that M/s. B S R & Co. LLP, (ICAI Firm Registration Number: 101248W/W- 100022) Statutory Auditors of Syngene Scientific Solutions Limited (“SSSL”), a material subsidiary of the Company, has tendered their resignation vide their letter dated July 07, 2026 from the position of Statutory Auditors of SSSL. A copy of the resignation letter dated July 07, 2026, as received from M/s. B S R & Co. LLP is attached herewith. The above information will also be available on the Company’s website at: www.syngeneintl.com. Kindly take this intimation on record. Thanking You, Yours faithfully, For SYNGENE INTERNATIONAL LIMITED Chethan Yogesh Company Secretary & Compliance Officer Encl: As above BS R &L LCPo . 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Pleraesfeteroo uorn godiinsgc uisncs oinonneswc ittoiuhocr no ntinaussa ttaitaouuntd oirtyo rs oft hCeo mpaAnspy e.dr i scussionsi,n tmetanoand lasiag guendm iwetinotttrhh as eu diotfo rs SyngIenntee rnaLtiimoitnthaeheldo ,l dcionmgp adnutyeom, a ndatoryo urfiror tmaa st ion of audiotfto hhreos l dcionmgpu anndyte hCreo mpaAnci2te0,s1 I 3nv. i eowft haeb owveew ,o uld nobtei nap osittcoio onnta issn tuaet auutdoiortfyto hCreos m pfoarnt yhy ee eanrd 3e1Md ar ch 202W7eh. a vaeld sios ctuhsmisaset dwt iettrhhM e a nageomfte hCneot m pany. Plefaisanetd t accohmepdlA entneedxA u,wr iert ehg atrhdie n tfoor mtaobt eio obnta biytn heed Compafrnoymt haeu difotrto hrrese sigansra etqiuobinySr eecdt Vi-ooDnf t he MSaEsBtIe r circnuol.Sa ErB I/HO/49/14/14(7)20d2a5t-3eC0dFJ Da-nPuoaDr2y/ I/23072662,/ 2026 pertatio'n Riensgi gonfsa ttaitaouuntd oifrrtoyoml r isse tnetdai nttdih emesai tre sruibasli diaries'. Asp etrhr ee quiorfte hmCeeo nmtp aAnci2te0,s1 w 3es, h ablefol r wartdhcieon pgoy ft hAeD T- 3a,sfi lweidRt OhC i,dn u ceo urse. Pleaacsceoe uprrte sigwniaittmhim oende iffaetcet . Youfrasi thfully, FoBr S& CRo L.L P ChartAecrceodu ntants ICAFIi rRme gisNturmabt1ei0ro1:n2 48W/W-100022 Partner MemberNso0h.9i 9p6 96 Regist,Jefrfeidc �: B 3 RC o3.( ap ar!ne.'s.hi'N1rlpmt R he g1str:a\tl81o�00 1�12 23) coinnvtBeoSrt Re d3,C o LLP (a !.l�iJho o:::re nc3r :1/i'il,i: ,1g1\ 1ido rCt hW in\gI,e se□ L:rnited U<1b1li,tvy1L tL;=,hPJR r"erge1nsrtir\p::J rnAooA nS a 18�1f)f ewfcirttoO hmc tob1e-rl IT? l!<r- l:\,l esCc2a1 1Nt<?esrt.e ::r'n< prHegshsw ay, 201.J Gorega\oEn. 1\sirllu mb.i, -J0006J BS R L&L PC o. AnnexAu re Discloofis nuforrem aftriotomhn se t atutoruyp oarnue dsiitgonra tion Sr.P articulars Details 1. Name of the listed entity/ material subsidiary Listed entity -Syngene International Limited Material subsidiary - Syngene Scientific Solutions Limited 2. Details of the statutory auditor: a. Name BS R& Co. LLP b. Address Embassy Golf Links Business Park, Pebble Beach, B Block, 3rdFl oor, No. 13/2, Off Intermediate Ring Road, Bengaluru -560071 C. Phone Number 8046823000 d. Email 3. Details of association with the listed entity/ Material subsidiary material subsidiary: a. Date on which the statutory auditor 21 July 2023 was aooointed b. Date on which the term of the statutory Conclusion of 6thA nnual General Meeting after auditor was scheduled to expire the financial year ended 3 1 March 2028 C. Prior to resignation, the latest audit Audit Report dated 28 April 2026 report/limited review report submitted by the auditor and date of its submission 4. Detailed reasons for resignation: Refer to the attached resignation letter 5. In case of any concerns, efforts made by the Not applicable auditor prior to resignation (including approaching the Audit Committee/Board of Directors along with the date of communication made to the Audit Committee/Board of Directors) 6. In case the information requested by the auditor was not provided, then following shall be disclosed: a. Whether the inability to obtain Not applicable sufficient appropriate audit evidence was due to a management - imposed limitation or circumstances beyond the control of the management. b. Whether the lack of information would Not applicable have significant impact on the financial statements/results. Sr.P articulars Details C. Whether the auditor has performed Not applicable alternative procedures to obtain appropriate evidence for the purposes of audit/limited review as laid down in SA 705 (Revised) d. Whether the lack of information was Not applicable prevalent in the previous reported financial statements/results. If yes, on what basis the previous audit/I imited review reports were issued. 7. Anv other facts relevant to the resismation: None Declaration: 1. We hereby confirm that the information given in this letter and its attachments is correct and complete. 2. We hereby confirm that there is no other material reason other than those provided above for resignation of my firm. / Yours faithfully, FoBrS R & CoL.L P ChartAecrceodu ntants ICAI Firm's Registration No: 101248W/W-100022 Partner Place: Bengaluru Date: 7 July 2026 - Membership No.: 099696