Resignation of Independent Director

Ref: Syn/CS/SE/Reg 30/2026-27/Jul/16 Syngene International Limited Biocon SEZ, Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area, IV Phase, Jigani Link Road, Bengaluru 560 099, Karnataka, India T +91 80 6891 9191 CIN: L85110KA1993PLC014937 July 29, 2026 www.syngeneintl.com To, To, The Manager, The Manager, BSE Limited National Stock Exchange of India Limited Corporate Relationship Department Corporate Communication Department Dalal Street, Mumbai – 400 001 Bandra (EAST), Mumbai – 400 051 Scrip Code: 539268 Scrip Symbol: SYNGENE Sub: Disclosure under Regulation 30 of the Securities and Exchange Board of India (Listing Obligations and Disclosure Requirements) Regulations, 2015 - Resignation of Independent Director Dear Sir/Madam, Pursuant to Regulation 30 of the SEBI (Listing Obligations and Disclosure Requirements Regulations, 2015 (“SEBI Listing Regulations”), read with Para A of Part A of Schedule III, we wish to inform you that Mr. Kush Parmar (DIN: 09212020) has tendered his resignation from the position of Independent Director of the Company, with effect from the close of business hours on July 29, 2026. Consequently, Mr. Parmar shall also cease to be a member of the Risk Management Committee, and the Science and Technology Committee of the Board. The Board places on record its sincere appreciation for Mr. Parmar’s valuable contributions and guidance during his tenure as an Independent Director. The Company has benefited immensely from his experience, independent judgment, and unwavering commitment. Disclosure pursuant to Regulation 30 read with Para A(7B) of Part A of Schedule III of SEBI Listing Regulations, 2015 and SEBI Master SEBI Circular no. SEBI/HO/49/14/14(7)2025-CFD- PoD2/I/3762/2026 dated 30 January 2026, is enclosed as an Annexure - 1. The letter of resignation received from Mr. Kush Parmar is enclosed herewith as an Annexure - 2. Further, in his letter, he had confirmed that there is no other material reason for his resignation other than those mentioned in his resignation letter. The above information will also be made available on the website of the Company at www.syngeneintl.com. Kindly take the above information on record. Thanking You, Yours faithfully, For SYNGENE INTERNATIONAL LIMITED Chethan Yogesh Company Secretary & Compliance Officer Encl: a/a Annexure - 1 Details as required under Regulation 30 read with Para A(7B) of Part A of Schedule III of SEBI (Listing Obligations and Disclosure Requirements) Regulations, 2015, and SEBI Master Circulars no. SEBI/HO/49/14/14(7)2025-CFD-PoD2/I/3762/2026 dated 30 January, 2026 are as under: S. Particulars Mr. Kush Parmar 1. Reason for change (viz. appointment, re- Resignation of Mr. Kush Parmar (DIN: appointment, resignation, removal, death or 09212020) owing to other existing & otherwise) increasing commitments in the USA and inability to devote sufficient time to the Company while residing outside India. 2. Date of appointment/re-appointment/cessation Effective from closure of business hours (as applicable) & term of appointment/re- on July 29, 2026. appointment; 3. Brief profile (in case of appointment) Not Applicable 4. Disclosure of relationships between directors (in Not Applicable case of appointment) Additional Information in case of resignation of an Independent Director as per Para A(7B) of Part A of Schedule III of SEBI Listing Regulations, 2015 5. Letter of Resignation along with detailed reason Copy of Resignation letter is enclosed as for resignation Annexure - 2 6. Names of listed entities in which the resigning Nil director holds directorships, indicating the category of directorship and membership of board committees, if any. 7. The independent director shall, along with the Mr. Kush Parmar had confirmed that there detailed reasons, also provide a confirmation are no material reasons for his resignation that there is no other material reasons other other than those mentioned in his than those provided. resignation letter. Annexure - 2