Ichnos Glenmark Innovation (IGI) to present updated clinical data for ISB 2001 (ABBV-2001) in Relapsed/ Refractory Mulitple Myeloma at 68th ASH Annual Meeting

November 4, 2026 To, To, National Stock Exchange of India Limited, BSE Limited, “Exchange Plaza”, Corporate Relationship Department, 5th Floor, Plot No. C/1, G Block, 2nd Floor, New Trading Ring, Bandra- Kurla Complex, Bandra (East), P.J. Towers, Dalal Street, Mumbai – 400 051 Mumbai – 400 001 Scrip Name: GLENMARK Scrip Code: 532296 ISIN: INE935A01035 ISIN: INE935A01035 Our Reference No. 63/26-27 Our Reference No. 63/26-27 Dear Sir/ Madam, Sub: Ichnos Glenmark Innovation (IGI) to Present Updated Clinical Data for ISB 2001 (ABBV 2001) in Relapsed/Refractory Multiple Myeloma at 68th ASH Annual Meeting Ichnos Glenmark Innovation (IGI) to Present Updated Clinical Data for ISB 2001 (ABBV-2001) in Relapsed/ Refractory Multiple Myeloma at 68th ASH Annual Meeting. - ISB 2001 (ABBV-2001) is an investigational first- and only-in-class CD38 × BCMA × CD3 trispecific T-cell engager. - Updated data from the Phase 1 TRIgnite-1 study include longer follow-up from the dose- escalation phase and early results from dose-expansion cohorts in patients with heavily pretreated multiple myeloma. Kindly find attached media release which is self- explanatory. Request you to take the same on record. Thanking you. For Glenmark Pharmaceuticals Limited Rashmi Khandelwal Company Secretary & Compliance Officer ACS – 28839 Encl: As above Glenmark Pharmaceuticals Limited Glenmark House, B D Sawant Marg, Andheri (E), Mumbai 400 099 T: 91 22 4018 9999 F: 91 22 4018 9988 CIN No: L24299MH1977PLC019982 W: www.glenmarkpharma.com Registered office: B/2, Mahalaxmi Chambers, 22 Bhulabhai Desai Road, Mumbai 400 026 E: complianceofficer@glenmarkpharma.com Ichnos Glenmark Innovation (IGI) to Present Updated Clinical Data for ISB 2001 (ABBV-2001) in Relapsed/Refractory Multiple Myeloma at 68th ASH Annual Meeting - ISB 2001 (ABBV-2001) is an investigational first- and only-in-class CD38 × BCMA × CD3 trispecific T-cell engager - Updated data from the Phase 1 TRIgnite-1 study include longer follow-up from the dose-escalation phase and early results from dose-expansion cohorts in patients with heavily pretreated multiple myeloma NEW YORK, NY, November 4, 2026: Ichnos Glenmark Innovation, Inc. (IGI), a global clinical-stage biotechnology company developing Multispecific™ therapeutics in oncology, today announced that updated clinical data from the Phase 1 study of ISB 2001 (ABBV-2001) in relapsed/refractory multiple myeloma (RRMM) will be presented as an oral presentation at the 68th American Society of Hematology (ASH) Annual Meeting. “With longer follow-up from dose escalation and initial results from dose expansion, ISB 2001 (ABBV-2001) continues to demonstrate robust efficacy and tolerability in heavily pretreated patients with relapsed/refractory multiple myeloma,” said Lida Pacaud, M.D., President and Chief Executive Officer of IGI. “These results represent an important milestone in the development of this first and only trispecific T-cell engager targeting CD38 x BCMA x CD3. Together with our partner, AbbVie, we remain focused on advancing ISB 2001 (ABBV-2001) as a potential new treatment option for patients with relapsed/refractory multiple myeloma (RRMM).” ISB 2001 (ABBV-2001) Oral Presentation: First- and only-in-class CD38 x BCMA x CD3 trispecific T-cell engager ISB 2001 (ABBV-2001): Updated Phase 1 (TRIgnite-1) study data demonstrate robust efficacy and tolerability in relapsed/refractory multiple myeloma (RRMM) Presenter: Binod Dhakal, M.D., Medical College of Wisconsin (MCW) Date & Time: Saturday, December 12, 2026, 4–4:15pm CST Room: La Nouvelle C at the Ernest N. Morial Convention Center, New Orleans Session: 654. Multiple Myeloma: Pharmacologic Therapies: The March of Immunotherapy About ISB 2001 (ABBV-2001) ISB 2001 (ABBV-2001) is an investigational first- and only-in-class trispecific T-cell engager targeting CD38 and BCMA on myeloma cells and CD3 on T cells that is in development for the treatment of relapsed/refractory multiple myeloma (RRMM). Engineered using IGI`s BEAT® Multispecific Platform, ISB 2001 (ABBV-2001) coordinates dual-antigen tumor recognition with immune engagement through T cells within a single molecular architecture. IGI and AbbVie formed an exclusive global licensing agreement for the trispecific in July 2025. ISB 2001 (ABBV- 2001) is being evaluated in multiple myeloma through the Phase 1 TRIgnite-1 study and a Phase 1/2 combination study. About IGI IGI is a global, fully integrated clinical-stage biotechnology company focused on developing innovative biologics in oncology. Headquartered in New York, NY, IGI is advancing a robust pipeline of novel, first-in-class Multispecifics™ aimed at addressing complex diseases and treating patients holistically. Powered by its proprietary BEAT® technology platform, IGI is committed to delivering breakthrough curative therapies to improve and extend the lives of patients battling hematological malignancies and solid tumors. For more information, visit www.IGInnovate.com. IGI Corporate Communications: Corporate.communications@IGInnovate.com