Resignation

Ref: Syn/CS/SE/Reg 30/2026-27/Sept/06 Syngene International Limited Biocon SEZ, Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area, IV Phase, Jigani Link Road, Bengaluru 560 099, Karnataka, India T +91 80 6891 9191 CIN: L85110KA1993PLC014937 September 21, 2026 www.syngeneintl.com To, To, The Manager, The Manager, BSE Limited National Stock Exchange of India Limited Corporate Relationship Department Corporate Communication Department Dalal Street, Mumbai – 400 001 Bandra (EAST), Mumbai – 400 051 Scrip Code: 539268 Scrip Symbol: SYNGENE Sub: Change in Senior Management Personnel - Disclosure under Regulation 30 of the Securities and Exchange Board of India (Listing Obligations and Disclosure Requirements) Regulations, 2015 Dear Sir/Madam, In compliance with Regulation 30 read with Schedule III, Part A, Para A (7) of the SEBI Listing Regulations, we hereby inform you that Mr. Pramuch Goel, Head Corporate Affairs & Communications and a member of Executive Committee (Senior Management Personnel) of the Company, as per Regulation 16(1)(d) of SEBI Listing Regulations, has resigned from the services of the Company w.e.f. close of business hours of September 21, 2026, to pursue other career opportunities. Details with respect to cessation of the SMP as required under Regulation 30(6) read with Para A (7) of Part A of Schedule III of the SEBI Listing Regulations and SEBI Circular no. SEBI/HO/49/14/14(7)2025- CFD-PoD2/I/3762/2026 dated 30 January 2026 issued in this regard, are given in Annexure A to this letter and a copy of resignation letter tendered by Mr. Pramuch Goel is also enclosed as Annexure B. The above information will also be made available on the website of the Company at www.syngeneintl.com. Kindly take the above information on record. Thanking You, Yours faithfully, For SYNGENE INTERNATIONAL LIMITED Chethan Yogesh Company Secretary & Compliance Officer Encl: a/a Annexure A Details as required under Regulation 30 read with Para A of Part A of Schedule III of SEBI (Listing Obligations and Disclosure Requirements) Regulations, 2015, and SEBI Circulars no. SEBI/HO/49/14/14(7)2025-CFD-PoD2/I/3762/2026 dated 30 January 2026 are as under: S. Particulars Pramuch Goel 1. Reason for change (viz. appointment, re- Mr. Pramuch Goel has resigned from the appointment, resignation, removal, death or services of the Company w.e.f. close of otherwise) business hours of September 21, 2026, to pursue other career opportunities. 2. Date of appointment/re-appointment/cessation Effective from close of business hours on (as applicable) & term of appointment/re- September 21, 2026. appointment; 3. Brief profile (in case of appointment) Not Applicable. 4. Disclosure of relationships between directors (in Not Applicable. case of appointment) Annexure B Septem1b52e,0r 2 6 MrS.i ddharth Mittal MD&CEO SyngeInnet ernLaitmiiotneald SubR:e signation DeaSri ddharth, Iw antteoid n foyrotmuh aIht a vdee citdore eds firgonmm yc urrpeonsti atsi' oHne oafd CorporAaftfeaa inrdCs o mmunicaatsiI ow nosu'll,di kteop ursouteh ecarr eer opportunitioefSs y nogueAtnssde ii.ds ec usmsyle adsw,to rkdianywg i blelM onday, Septem2b12e,0r 2 6. Iw oullidtk ote h aynokfu o arly lo usru ppoIar ltsw.oa nttot haKnrika Mna zumdar-Shaw, ouErx ecuCthiavier pearnsdto hnBe,o arfdog ri vmient gh oep porttuoln eiatarynn d contraitSb yuntgee ne. Iw isShy ngeanntedh een ttieraecm o ntisnuucecdae nsgdsr owth. Regards, PramuGcohe l